Calcium fluoride based multifunctional nanoparticles for multimodal imaging

• Marion Straßer,
• Joachim H. X. Schrauth,
• Sofia Dembski,
• Daniel Haddad,
• Bernd Ahrens,
• Stefan Schweizer,
• Bastian Christ,
• Alevtina Cubukova,
• Marco Metzger,
• Heike Walles,
• Peter M. Jakob and
• Gerhard Sextl

Beilstein J. Nanotechnol. 2017, 8, 1484–1493, doi:10.3762/bjnano.8.148

• synthesis and determine the long-term stability of the CAs. No cytotoxicity of NP concentrations between 0.5 and 1 mg·mL−1 was observed after exposure to human dermal fibroblasts over 24 h. Overall this study shows, that the CaF2:(Tb3+,Gd3+) NPs are suitable for medical imaging. Keywords: calcium fluoride

• nanoparticles; magnetic resonance imaging (MRI); multifunctional nanoparticles; multimodal imaging; photoluminescence; Introduction In recent years, medical imaging has become an important approach in the fields of diagnostics, therapy and regenerative medicine. Besides the classical technology of X-ray

Exploring the retention properties of CaF₂ nanoparticles as possible additives for dental care application with tapping-mode atomic force microscope in liquid

• Matthias Wasem,
• Joachim Köser,
• Sylvia Hess,
• Enrico Gnecco and
• Ernst Meyer

Beilstein J. Nanotechnol. 2014, 5, 36–43, doi:10.3762/bjnano.5.4

• upon exposure to a fluorated solution has been observed with AFM in liquid [26]. To the best of our knowledge no manipulation experiment of particles adsorbed on human tooth enamel has been performed so far. The anticaries activity of calcium fluoride nanoparticles is mainly determined by two factors

• adhesion strength of calcium fluoride nanoparticles adsorbed on mica and on tooth enamel in liquid with AM-AFM. Theory As already described above, manipulation experiments in the tapping-mode are difficult to quantify as dynamic and friction processes are involved at the same time. To connect the power

• layer (hydrodynamic drag of water layer), but the intrinsic particle–sample interaction energies. The frequency distribution of the calculated power dissipated for each of the particles enables us to examine the chemical affinity between the calcium fluoride nanoparticles adsorbed on mica and on